NeuroUrology Labs Led by Drs. Jim Hokanson and Aaron Mickle

Research

Highlighted

Open collaborative writing with Manubot
Open collaborative writing with Manubot
Daniel S. Himmelstein, Vincent Rubinetti, David R. Slochower, Dongbo Hu, Venkat S. Malladi, Casey S. Greene, Anthony Gitter
PLOS Computational Biology  ·  04 Dec 2020  ·  doi:10.1371/journal.pcbi.1007128
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Website
open-science collaboration

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2026

The LURN urinary urgency and lifestyle wearable tracker ULTra study: Design and feasibility
The LURN urinary urgency and lifestyle wearable tracker (ULTra) study: Design and feasibility
Catherine S. Bradley, James A. Hokanson, Shelby L. Francis, Brian Bieber, Deepika Laddu, …, Brian T. Helfand, Calvin Andrews, John Graff, Ziya Kirkali, Karl J. Kreder
Continence  ·  01 Sep 2026  ·  doi:10.1016/j.cont.2026.102473
A Stretchable Optogenetic Probe for Wireless Control of Bladder Nociception
A Stretchable Optogenetic Probe for Wireless Control of Bladder Nociception
Janghoon Joo, Hannah A. Anderson, Wooseok Kim, Shane H. Priester, Bogeun Kim, …, Joohoon Kang, Geumbee Lee, Jae-Young Yoo, Aaron D. Mickle, Sang Min Won
Engineering  ·  01 Apr 2026  ·  doi:10.1016/j.eng.2026.03.020
Lessons learned from conducting a multi-center lower urinary tract physiology study: the LURN experience
Lessons learned from conducting a multi-center lower urinary tract physiology study: the LURN experience
Claire C. Yang, James A. Hokanson, Anna C. Kirby, Brenda W. Gillespie, H. Henry Lai, Karl J. Kreder, C. Emi Bretschneider, Ziya Kirkali, John O.L. Delancey
Continence  ·  01 Mar 2026  ·  doi:10.1016/j.cont.2026.102320

2025

Contractions of ex-vivo mouse bladder driven by activation of channelrhodopsin-2 expressed in urothelial cells
Contractions of ex-vivo mouse bladder driven by activation of channelrhodopsin-2 expressed in urothelial cells
Firoj Alom, Kyle Joseph Ratcliff, Bhavana Talluri, Aaron D. Mickle
Scientific Reports  ·  03 Oct 2025  ·  doi:10.1038/s41598-025-18216-2
Sexual function in women with bothersome lower urinary tract symptoms: findings from the symptoms of lower urinary tract dysfunction research network LURN cohort study
Sexual function in women with bothersome lower urinary tract symptoms: findings from the symptoms of lower urinary tract dysfunction research network (LURN) cohort study
C Emi Bretschneider, Caroline Smerdon, Brian Bieber, Nathan Goodrich, James Griffith, …, Magaly Guerrero, Sreya Gutta, Kathryn E Flynn, Karen John, Catherine S Bradley
The Journal of Sexual Medicine  ·  24 Apr 2025  ·  doi:10.1093/jsxmed/qdaf063
Expanded Physiological Testing of the Lower Urinary Tract in Asymptomatic Women and Those With Urgency Urinary Incontinence: Findings From the LURN Organ Study
Expanded Physiological Testing of the Lower Urinary Tract in Asymptomatic Women and Those With Urgency Urinary Incontinence: Findings From the LURN‐Organ Study
James A. Hokanson, John O. L. DeLancey, Anna C. Kirby, Brenda Gillespie, H. Henry Lai, …, Linda Black, Sarah Richardson, Kimberly Kenton, Ziya Kirkali, Claire C. Yang
Neurourology and Urodynamics  ·  31 Mar 2025  ·  doi:10.1002/nau.70038
Liquid-based encapsulation for implantable bioelectronics across broad pH environments
Liquid-based encapsulation for implantable bioelectronics across broad pH environments
He Sun, Xiaoting Xue, Gabriella L. Robilotto, Xincheng Zhang, ChangHee Son, …, Jie He, Xueju Wang, Yan Li, Aaron D. Mickle, Yi Zhang
Nature Communications  ·  25 Jan 2025  ·  doi:10.1038/s41467-025-55992-x

2024

Faster bladder filling in rats reduces detrusor overactivity but worsens i.e., decreases bladder compliance
Faster bladder filling in rats reduces detrusor overactivity but worsens (i.e., decreases) bladder compliance
Wei He, Nick Slavik, Jacob Braun, Farshad Samadifam, James A. Hokanson
American Journal of Physiology-Renal Physiology  ·  01 Dec 2024  ·  doi:10.1152/ajprenal.00209.2024
Role of local angiotensin II signaling in bladder function
Role of local angiotensin II signaling in bladder function
Hannah A. Anderson, Gabriella L. Robilotto, Aaron D. Mickle
American Journal of Physiology-Renal Physiology  ·  01 Nov 2024  ·  doi:10.1152/ajprenal.00204.2024
Structural Changes in Brain White Matter Tracts Associated With Overactive Bladder Revealed by Diffusion Tensor Magnetic Resonance Imaging: Findings From a Symptoms of Lower Urinary Tract Dysfunction Research Network Cross-Sectional Case-Control Study
Structural Changes in Brain White Matter Tracts Associated With Overactive Bladder Revealed by Diffusion Tensor Magnetic Resonance Imaging: Findings From a Symptoms of Lower Urinary Tract Dysfunction Research Network Cross-Sectional Case-Control Study
H. Henry Lai, Jerrel Rutlin, Abigail R. Smith, Margaret E. Helmuth, James A. Hokanson, …, Kimberly Kenton, John O. L. DeLancey, Karen John, Ziya Kirkali, Joshua S. Shimony
Journal of Urology  ·  01 Aug 2024  ·  doi:10.1097/ju.0000000000004022
Predicting success using response after lead implantation with sacral neuromodulation for urgency incontinence
Predicting success using response after lead implantation with sacral neuromodulation for urgency incontinence
Whitney K. Hendrickson, Chong Zhang, James A. Hokanson, Ingrid E. Nygaard, Angela P. Presson
Neurourology and Urodynamics  ·  29 Jul 2024  ·  doi:10.1002/nau.25562
Developing a urinary incontinence primary care pathway: a mixed methods study
Developing a urinary incontinence primary care pathway: a mixed methods study
Marie C Luebke, Joan M Neuner, Joanna Balza, Emily R W Davidson, James A Hokanson, Sarah Marowski, Robert Corey O’Connor, Emily Schmitt, Aaron N Winn, Kathryn E Flynn
Family Practice  ·  19 Jul 2024  ·  doi:10.1093/fampra/cmae035
Acute ampakines increase voiding function and coordination in a rat model of SCI
Acute ampakines increase voiding function and coordination in a rat model of SCI
Sabhya Rana, Firoj Alom, Robert C Martinez, David D Fuller, Aaron D Mickle
eLife  ·  07 Mar 2024  ·  doi:10.7554/eLife.89767
Acute ampakines increase voiding function and coordination in a rat model of SCI
Acute ampakines increase voiding function and coordination in a rat model of SCI
Sabhya Rana, Firoj Alom, Robert C Martinez, David D Fuller, Aaron D Mickle
eLife Sciences Publications, Ltd  ·  19 Feb 2024  ·  doi:10.7554/eLife.89767.2
Hypertension and urologic chronic pelvic pain syndrome: An analysis of MAPP-I data
Hypertension and urologic chronic pelvic pain syndrome: An analysis of MAPP-I data
Rosalynn R.Z. Conic, Terrie Vasilopoulos, Karthik Devulapally, Rene Przkora, Andrew Dubin, Kimberly T. Sibille, Aaron D. Mickle
BMC Urology  ·  28 Jan 2024  ·  doi:10.1186/s12894-024-01407-w

2023

Pathways and parameters of sacral neuromodulation in rats
Pathways and parameters of sacral neuromodulation in rats
James A. Hokanson, Christopher L. Langdale, Warren M. Grill
American Journal of Physiology-Renal Physiology  ·  01 Dec 2023  ·  doi:10.1152/ajprenal.00123.2023
National Urogynecology Research Agenda: A Path Forward for Advancing the Treatment and Management of Pelvic Floor Disorders
National Urogynecology Research Agenda: A Path Forward for Advancing the Treatment and Management of Pelvic Floor Disorders
Gena C. Dunivan, Mary F. Ackenbom, Marianna Alperin, Jennifer T. Anger, Danielle D. Antosh, …, Jens-Erik Walter, Eva K. Welch, Alan J. Wolfe, Aldene Zeno, Colleen D. McDermott
Urogynecology  ·  01 Nov 2023  ·  doi:10.1097/spv.0000000000001427
Optogenetic urothelial cell stimulation induces bladder contractions and pelvic nerve afferent firing
Optogenetic urothelial cell stimulation induces bladder contractions and pelvic nerve afferent firing
Gabriella L. Robilotto, Olivia J. Yang, Firoj Alom, Richard D. Johnson, Aaron D. Mickle
American Journal of Physiology-Renal Physiology  ·  01 Aug 2023  ·  doi:10.1152/ajprenal.00035.2023
Evaluating the transduction efficiency of systemically delivered AAV vectors in the rat nervous system
Evaluating the transduction efficiency of systemically delivered AAV vectors in the rat nervous system
Olivia J. Yang, Gabriella L. Robilotto, Firoj Alom, Karla Alemán, Karthik Devulapally, Abigail Morris, Aaron D. Mickle
Frontiers in Neuroscience  ·  23 Jan 2023  ·  doi:10.3389/fnins.2023.1001007

2022

Reply to: The case against urethral failure is not a critical factor in female urinary incontinence. Now what The integral theory system
Reply to: The case against urethral failure is not a critical factor in female urinary incontinence. Now what? The integral theory system
John O. DeLancey, James A. Hokanson
Neurourology and Urodynamics  ·  01 Sep 2022  ·  doi:10.1002/nau.25036
Role of Src kinase in regulating protein kinase C mediated phosphorylation of scp TRPV1 scp
Role of Src kinase in regulating protein kinase C mediated phosphorylation of TRPV1
Gabriella L. Robilotto, Durga P. Mohapatra, Andrew J. Shepherd, Aaron D. Mickle
European Journal of Pain  ·  04 Aug 2022  ·  doi:10.1002/ejp.2017
Noncancerous Genitourinary Conditions as a Public Health Priority: Conceptualizing the Hidden Burden
Noncancerous Genitourinary Conditions as a Public Health Priority: Conceptualizing the Hidden Burden
Sonya S. Brady, Tamara G. Bavendam, Christine K. Bradway, Britt Conroy, Annemarie Dowling-Castronovo, …, Jenna M. Norton, William Stuart Reynolds, Siobhan Sutcliffe, Nicole Zhang, James A. Hokanson
Urology  ·  01 Aug 2022  ·  doi:10.1016/j.urology.2021.08.040
Open source timed pressure control hardware and software for delivery of air mediated distensions in animal models
Open source timed pressure control hardware and software for delivery of air mediated distensions in animal models
Trishna Patel, Jamie Hendren, Nathan Lee, Aaron D. Mickle
HardwareX  ·  01 Apr 2022  ·  doi:10.1016/j.ohx.2022.e00271
Machine Learning for Urodynamic Detection of Detrusor Overactivity
Machine Learning for Urodynamic Detection of Detrusor Overactivity
Kevin T. Hobbs, Nathaniel Choe, Leonid I. Aksenov, Lourdes Reyes, Wilkins Aquino, Jonathan C. Routh, James A. Hokanson
Urology  ·  01 Jan 2022  ·  doi:10.1016/j.urology.2021.09.027

2021

Advancing our understanding of the neural control of the female human urethra
Advancing our understanding of the neural control of the female human urethra
Claire C. Yang, James A. Hokanson, Janet R. Keast
Neurourology and Urodynamics  ·  04 Oct 2021  ·  doi:10.1002/nau.24807
Effects of intravesical prostaglandin E sub 2 sub on bladder function are preserved in capsaicin-desensitized rats
Effects of intravesical prostaglandin E2 on bladder function are preserved in capsaicin-desensitized rats
James A. Hokanson, Christopher L. Langdale, Philip H. Milliken, Arun Sridhar, Warren M. Grill
American Journal of Physiology-Renal Physiology  ·  01 Feb 2021  ·  doi:10.1152/ajprenal.00302.2020

2020

Open collaborative writing with Manubot
Open collaborative writing with Manubot
Daniel S. Himmelstein, Vincent Rubinetti, David R. Slochower, Dongbo Hu, Venkat S. Malladi, Casey S. Greene, Anthony Gitter
PLOS Computational Biology  ·  04 Dec 2020  ·  doi:10.1371/journal.pcbi.1007128
Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt ut labore et dolore magna aliqua.
Manubot
Manuscript Source
Website
open-science collaboration
Characterization of a method to study urodynamics and bladder nociception in male and female mice
Characterization of a method to study urodynamics and bladder nociception in male and female mice
Paulome Srivastava, Henry H. Lai, Aaron D. Mickle
LUTS: Lower Urinary Tract Symptoms  ·  17 Nov 2020  ·  doi:10.1111/luts.12365
Stimulation of the pelvic nerve increases bladder capacity in the PGE sub 2 sub cat model of overactive bladder
Stimulation of the pelvic nerve increases bladder capacity in the PGE 2 cat model of overactive bladder
Christopher L. Langdale, James A. Hokanson, Philip H. Milliken, Arun Sridhar, Warren M. Grill
American Journal of Physiology-Renal Physiology  ·  01 Jun 2020  ·  doi:10.1152/ajprenal.00068.2020
Constructing knowledge graphs and their biomedical applications
Constructing knowledge graphs and their biomedical applications
David N. Nicholson, Casey S. Greene
Computational and Structural Biotechnology Journal  ·  01 Jan 2020  ·  doi:10.1016/j.csbj.2020.05.017

2019

Battery-free, fully implantable optofluidic cuff system for wireless optogenetic and pharmacological neuromodulation of peripheral nerves
Battery-free, fully implantable optofluidic cuff system for wireless optogenetic and pharmacological neuromodulation of peripheral nerves
Yi Zhang, Aaron D. Mickle, Philipp Gutruf, Lisa A. McIlvried, Hexia Guo, …, Jonathan T. Reeder, Sherri K. Vogt, Yonggang Huang, John A. Rogers, Robert W. Gereau
Science Advances  ·  05 Jul 2019  ·  doi:10.1126/sciadv.aaw5296
A pilot study investigating the effects of intraurethral stimulation and the potential to prevent urgency urinary incontinence episodes in women
A pilot study investigating the effects of intraurethral stimulation and the potential to prevent urgency urinary incontinence episodes in women
James A Hokanson, Warren Grill, Cindy Amundsen
Center for Open Science  ·  03 Jul 2019  ·  doi:10.31219/osf.io/fdrv4
A wireless closed-loop system for optogenetic peripheral neuromodulation
A wireless closed-loop system for optogenetic peripheral neuromodulation
Aaron D. Mickle, Sang Min Won, Kyung Nim Noh, Jangyeol Yoon, Kathleen W. Meacham, …, H. Henry Lai, Yonggang Huang, Sung-Il Park, Robert W. Gereau, John A. Rogers
Nature  ·  02 Jan 2019  ·  doi:10.1038/s41586-018-0823-6

2018

A bright future Optogenetics in the periphery for pain research and therapy
A bright future? Optogenetics in the periphery for pain research and therapy
Aaron D. Mickle, Robert W. Gereau
Pain  ·  01 Sep 2018  ·  doi:10.1097/j.pain.0000000000001329
An open-source platform for analyzing and sharing worm-behavior data
An open-source platform for analyzing and sharing worm-behavior data
Avelino Javer, Michael Currie, Chee Wai Lee, Jim Hokanson, Kezhi Li, …, QueeLim Ch’ng, William R. Schafer, Ellen A. A. Nollen, Rex Kerr, André E. X. Brown
Nature Methods  ·  31 Aug 2018  ·  doi:10.1038/s41592-018-0112-1
Effects of Synchronous Electrode Pulses on Neural Recruitment During Multichannel Microstimulation
Effects of Synchronous Electrode Pulses on Neural Recruitment During Multichannel Microstimulation
James A. Hokanson, Robert A. Gaunt, Douglas J. Weber
Scientific Reports  ·  30 Aug 2018  ·  doi:10.1038/s41598-018-31247-2
Macrophage angiotensin II type 2 receptor triggers neuropathic pain
Macrophage angiotensin II type 2 receptor triggers neuropathic pain
Andrew J. Shepherd, Aaron D. Mickle, Judith P. Golden, Madison R. Mack, Carmen M. Halabi, …, Vijay K. Samineni, Brian S. Kim, Eric G. Krause, Robert W. Gereau, Durga P. Mohapatra
Proceedings of the National Academy of Sciences  ·  06 Aug 2018  ·  doi:10.1073/pnas.1721815115
Detection of Bladder Contractions From the Activity of the External Urethral Sphincter in Rats Using Sparse Regression
Detection of Bladder Contractions From the Activity of the External Urethral Sphincter in Rats Using Sparse Regression
Erica M. Rutter, Christopher L. Langdale, James A. Hokanson, Franz Hamilton, Hien Tran, Warren M. Grill, Kevin B. Flores
IEEE Transactions on Neural Systems and Rehabilitation Engineering  ·  01 Aug 2018  ·  doi:10.1109/TNSRE.2018.2854675
Angiotensin II Triggers Peripheral Macrophage-to-Sensory Neuron Redox Crosstalk to Elicit Pain
Angiotensin II Triggers Peripheral Macrophage-to-Sensory Neuron Redox Crosstalk to Elicit Pain
Andrew J. Shepherd, Bryan A. Copits, Aaron D. Mickle, Páll Karlsson, Suraj Kadunganattil, …, Gregory Dussor, Eric G. Krause, Theodore J. Price, Robert W. Gereau, Durga P. Mohapatra
The Journal of Neuroscience  ·  05 Jul 2018  ·  doi:10.1523/JNEUROSCI.3542-17.2018
Natural Wax for Transient Electronics
Natural Wax for Transient Electronics
Sang Min Won, Jahyun Koo, Kaitlyn E. Crawford, Aaron D. Mickle, Yeguang Xue, …, Hokyung Jang, Matthew R. MacEwan, Yonggang Huang, Robert W. Gereau, John A. Rogers
Advanced Functional Materials  ·  25 Jun 2018  ·  doi:10.1002/adfm.201801819
Parathyroid hormone related peptide activates and modulates scp TRPV scp 1 channel in human scp DRG scp neurons
Parathyroid hormone‐related peptide activates and modulates TRPV1 channel in human DRG neurons
A.J. Shepherd, A.D. Mickle, L.A. McIlvried, R.W. Gereau, D.P. Mohapatra
European Journal of Pain  ·  11 Jun 2018  ·  doi:10.1002/ejp.1251
Stimulation of the sensory pudendal nerve increases bladder capacity in the rat
Stimulation of the sensory pudendal nerve increases bladder capacity in the rat
James A. Hokanson, Christopher L. Langdale, Arun Sridhar, Warren M. Grill
American Journal of Physiology-Renal Physiology  ·  01 Apr 2018  ·  doi:10.1152/ajprenal.00373.2017
Sci-Hub provides access to nearly all scholarly literature
Sci-Hub provides access to nearly all scholarly literature
Daniel S Himmelstein, Ariel Rodriguez Romero, Jacob G Levernier, Thomas Anthony Munro, Stephen Reid McLaughlin, Bastian Greshake Tzovaras, Casey S Greene
eLife  ·  01 Mar 2018  ·  doi:10.7554/eLife.32822
Parathyroid Hormone-Related Peptide Elicits Peripheral TRPV1-dependent Mechanical Hypersensitivity
Parathyroid Hormone-Related Peptide Elicits Peripheral TRPV1-dependent Mechanical Hypersensitivity
Andrew J. Shepherd, Aaron D. Mickle, Suraj Kadunganattil, Hongzhen Hu, Durga P. Mohapatra
Frontiers in Cellular Neuroscience  ·  15 Feb 2018  ·  doi:10.3389/fncel.2018.00038

2017

Miniaturized, Battery Free Optofluidic Systems with Potential for Wireless Pharmacology and Optogenetics
Miniaturized, Battery‐Free Optofluidic Systems with Potential for Wireless Pharmacology and Optogenetics
Kyung Nim Noh, Sung Il Park, Raza Qazi, Zhanan Zou, Aaron D. Mickle, …, Kyung‐In Jang, Robert W. Gereau, Jianliang Xiao, John A. Rogers, Jae‐Woong Jeong
Small  ·  07 Dec 2017  ·  doi:10.1002/smll.201702479
Optogenetic silencing of nociceptive primary afferents reduces evoked and ongoing bladder pain
Optogenetic silencing of nociceptive primary afferents reduces evoked and ongoing bladder pain
Vijay K. Samineni, Aaron D. Mickle, Jangyeol Yoon, Jose G. Grajales-Reyes, Melanie Y. Pullen, …, Graydon B. Gereau, Sherri K. Vogt, H. Henry Lai, John A. Rogers, Robert W. Gereau
Scientific Reports  ·  20 Nov 2017  ·  doi:10.1038/s41598-017-16129-3
OAB without an overactive bladder in the acute prostaglandin E2 rat model
OAB without an overactive bladder in the acute prostaglandin E2 rat model
James A. Hokanson, Christopher L. Langdale, Arun Sridhar, Warren M. Grill
American Journal of Physiology-Renal Physiology  ·  01 Nov 2017  ·  doi:10.1152/ajprenal.00270.2017
Stimulation of the pelvic nerve increases bladder capacity in the prostaglandin E sub 2 sub rat model of overactive bladder
Stimulation of the pelvic nerve increases bladder capacity in the prostaglandin E2 rat model of overactive bladder
Christopher L. Langdale, James A. Hokanson, Arun Sridhar, Warren M. Grill
American Journal of Physiology-Renal Physiology  ·  01 Sep 2017  ·  doi:10.1152/ajprenal.00116.2017
Macrophage-to-sensory neuron crosstalk mediated by Angiotensin II type-2 receptor elicits neuropathic pain
Macrophage-to-sensory neuron crosstalk mediated by Angiotensin II type-2 receptor elicits neuropathic pain
Andrew J. Shepherd, Aaron D. Mickle, Bryan A. Copits, Páll Karlsson, Suraj Kadunganattil, …, Brian S. Kim, Eric G. Krause, Theodore J. Price, Robert W. Gereau, Durga P. Mohapatra
openRxiv  ·  25 Aug 2017  ·  doi:10.1101/166546
Fully implantable, battery-free wireless optoelectronic devices for spinal optogenetics
Fully implantable, battery-free wireless optoelectronic devices for spinal optogenetics
Vijay K. Samineni, Jangyeol Yoon, Kaitlyn E. Crawford, Yu Ra Jeong, Kajanna C McKenzie, …, Anthony Banks, Jeong Sook Ha, Judith P. Golden, John A. Rogers, Robert W. Gereau
Pain  ·  08 Jun 2017  ·  doi:10.1097/j.pain.0000000000000968
Real-time decoding of bladder pressure from pelvic nerve activity
Real-time decoding of bladder pressure from pelvic nerve activity
Carl Lubba, Elie Mitrani, Jim Hokanson, Warren M. Grill, Simon R. Schultz
2017 8th International IEEE/EMBS Conference on Neural Engineering (NER)  ·  01 May 2017  ·  doi:10.1109/NER.2017.8008427
Neuroprosthetic Control of Lower Urinary Tract Function
Neuroprosthetic Control of Lower Urinary Tract Function
James A. Hokanson, Cindy L. Amundsen, Warren M. Grill
Series on Bioengineering and Biomedical Engineering  ·  15 Mar 2017  ·  doi:10.1142/9789813207158_0017
Flexible Near-Field Wireless Optoelectronics as Subdermal Implants for Broad Applications in Optogenetics
Flexible Near-Field Wireless Optoelectronics as Subdermal Implants for Broad Applications in Optogenetics
Gunchul Shin, Adrian M. Gomez, Ream Al-Hasani, Yu Ra Jeong, Jeonghyun Kim, …, Yonggang Huang, Robert W. Gereau, Jeong Sook Ha, Michael R. Bruchas, John A. Rogers
Neuron  ·  01 Feb 2017  ·  doi:10.1016/j.neuron.2016.12.031

2016

Stretchable multichannel antennas in soft wireless optoelectronic implants for optogenetics
Stretchable multichannel antennas in soft wireless optoelectronic implants for optogenetics
Sung Il Park, Gunchul Shin, Jordan G. McCall, Ream Al-Hasani, Aaron Norris, …, Gregory Dussor, Theodore J. Price, Robert W. Gereau, Michael R. Bruchas, John A. Rogers
Proceedings of the National Academy of Sciences  ·  28 Nov 2016  ·  doi:10.1073/pnas.1611769113
Nociceptive TRP Channels: Sensory Detectors and Transducers in Multiple Pain Pathologies
Nociceptive TRP Channels: Sensory Detectors and Transducers in Multiple Pain Pathologies
Aaron Mickle, Andrew Shepherd, Durga Mohapatra
Pharmaceuticals  ·  14 Nov 2016  ·  doi:10.3390/ph9040072

2015

Induction of thermal and mechanical hypersensitivity by parathyroid hormone related peptide through upregulation of TRPV1 function and trafficking
Induction of thermal and mechanical hypersensitivity by parathyroid hormone–related peptide through upregulation of TRPV1 function and trafficking
Aaron D. Mickle, Andrew J. Shepherd, Lipin Loo, Durga P. Mohapatra
Pain  ·  01 Sep 2015  ·  doi:10.1097/j.pain.0000000000000224
Neuroprostheses for somatosensory function
Neuroprostheses for somatosensory function
L.E. Fisher, J.A. Hokanson, D.J. Weber
Implantable Neuroprostheses for Restoring Function  ·  01 Jan 2015  ·  doi:10.1016/B978-1-78242-101-6.00006-9
Sensory TRP Channels
Sensory TRP Channels
Aaron D. Mickle, Andrew J. Shepherd, Durga P. Mohapatra
Progress in Molecular Biology and Translational Science  ·  01 Jan 2015  ·  doi:10.1016/bs.pmbts.2015.01.002

2014

NMDA receptor mediates chronic visceral pain induced by neonatal noxious somatic stimulation
NMDA receptor mediates chronic visceral pain induced by neonatal noxious somatic stimulation
Adrian Miranda, Aaron Mickle, Mitchell Bruckert, Pradeep Kannampalli, Banani Banerjee, Jyoti N. Sengupta
European Journal of Pharmacology  ·  01 Dec 2014  ·  doi:10.1016/j.ejphar.2014.09.034
OpenWorm: an open-science approach to modeling Caenorhabditis elegans
OpenWorm: an open-science approach to modeling Caenorhabditis elegans
Balázs Szigeti, Padraig Gleeson, Michael Vella, Sergey Khayrulin, Andrey Palyanov, Jim Hokanson, Michael Currie, Matteo Cantarelli, Giovanni Idili, Stephen Larson
Frontiers in Computational Neuroscience  ·  03 Nov 2014  ·  doi:10.3389/fncom.2014.00137
Interference With Peroxisome Proliferator-Activated Receptor-γ in Vascular Smooth Muscle Causes Baroreflex Impairment and Autonomic Dysfunction
Interference With Peroxisome Proliferator-Activated Receptor-γ in Vascular Smooth Muscle Causes Baroreflex Impairment and Autonomic Dysfunction
Giulianna R. Borges, Donald A. Morgan, Pimonrat Ketsawatsomkron, Aaron D. Mickle, Anthony P. Thompson, Martin D. Cassell, Durga P. Mohapatra, Kamal Rahmouni, Curt D. Sigmund
Hypertension  ·  01 Sep 2014  ·  doi:10.1161/HYPERTENSIONAHA.114.03553
Visceral analgesic effect of 5-HT4 receptor agonist in rats involves the rostroventral medulla RVM
Visceral analgesic effect of 5-HT4 receptor agonist in rats involves the rostroventral medulla (RVM)
Jyoti N. Sengupta, Aaron Mickle, Pradeep Kannampalli, Russell Spruell, John McRorie, Reza Shaker, Adrian Miranda
Neuropharmacology  ·  01 Apr 2014  ·  doi:10.1016/j.neuropharm.2013.12.006

2012

Distinct Modifications in Kv2.1 Channel via Chemokine Receptor CXCR4 Regulate Neuronal Survival-Death Dynamics
Distinct Modifications in Kv2.1 Channel via Chemokine Receptor CXCR4 Regulate Neuronal Survival-Death Dynamics
Andrew J. Shepherd, Lipin Loo, Raeesa P. Gupte, Aaron D. Mickle, Durga P. Mohapatra
The Journal of Neuroscience  ·  05 Dec 2012  ·  doi:10.1523/JNEUROSCI.3029-12.2012
Pronociceptive effect of 5-HT1A receptor agonist on visceral pain involves spinal N-methyl-d-aspartate NMDA receptor
Pronociceptive effect of 5-HT1A receptor agonist on visceral pain involves spinal N-methyl-d-aspartate (NMDA) receptor
A. Mickle, P. Kannampalli, M. Bruckert, A. Miranda, B. Banerjee, J.N. Sengupta
Neuroscience  ·  01 Sep 2012  ·  doi:10.1016/j.neuroscience.2012.05.030
The C-Type Natriuretic Peptide Induces Thermal Hyperalgesia through a Noncanonical Gβγ-dependent Modulation of TRPV1 Channel
The C-Type Natriuretic Peptide Induces Thermal Hyperalgesia through a Noncanonical Gβγ-dependent Modulation of TRPV1 Channel
Lipin Loo, Andrew J. Shepherd, Aaron D. Mickle, Ramón A. Lorca, Leonid P. Shutov, Yuriy M. Usachev, Durga P. Mohapatra
The Journal of Neuroscience  ·  29 Aug 2012  ·  doi:10.1523/JNEUROSCI.1330-12.2012

2011

Limb-State Information Encoded by Peripheral and Central Somatosensory Neurons: Implications for an Afferent Interface
Limb-State Information Encoded by Peripheral and Central Somatosensory Neurons: Implications for an Afferent Interface
Douglas J. Weber, Brian M. London, James A. Hokanson, Christopher A. Ayers, Robert A. Gaunt, Ricardo R. Torres, Boubker Zaaimi, Lee E. Miller
IEEE Transactions on Neural Systems and Rehabilitation Engineering  ·  01 Oct 2011  ·  doi:10.1109/TNSRE.2011.2163145
A computational model for estimating recruitment of primary afferent fibers by intraneural stimulation in the dorsal root ganglia
A computational model for estimating recruitment of primary afferent fibers by intraneural stimulation in the dorsal root ganglia
D J Bourbeau, J A Hokanson, J E Rubin, D J Weber
Journal of Neural Engineering  ·  16 Aug 2011  ·  doi:10.1088/1741-2560/8/5/056009
Effects of spatial and temporal parameters of primary afferent microstimulation on neural responses evoked in primary somatosensory cortex of an anesthetized cat
Effects of spatial and temporal parameters of primary afferent microstimulation on neural responses evoked in primary somatosensory cortex of an anesthetized cat
J. A. Hokanson, C. A. Ayers, R. A. Gaunt, T. M. Bruns, D. J. Weber
2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society  ·  01 Aug 2011  ·  doi:10.1109/IEMBS.2011.6091857
Neonatal cystitis-induced colonic hypersensitivity in adult rats: a model of viscero-visceral convergence
Neonatal cystitis-induced colonic hypersensitivity in adult rats: a model of viscero-visceral convergence
A. Miranda, A. Mickle, J. Schmidt, Z. Zhang, R. Shaker, B. Banerjee, J. N. Sengupta
Neurogastroenterology & Motility  ·  18 May 2011  ·  doi:10.1111/j.1365-2982.2011.01724.x

2010

Antinociceptive effects of melatonin in a rat model of post-inflammatory visceral hyperalgesia: A centrally mediated process
Antinociceptive effects of melatonin in a rat model of post-inflammatory visceral hyperalgesia: A centrally mediated process
Aaron Mickle, Manu Sood, Zhihong Zhang, Golbon Shahmohammadi, Jyoti N. Sengupta, Adrian Miranda
Pain  ·  01 Jun 2010  ·  doi:10.1016/j.pain.2010.03.030

2009

Microstimulation of primary afferent neurons in the L7 dorsal root ganglia using multielectrode arrays in anesthetized cats: thresholds and recruitment properties
Microstimulation of primary afferent neurons in the L7 dorsal root ganglia using multielectrode arrays in anesthetized cats: thresholds and recruitment properties
R A Gaunt, J A Hokanson, D J Weber
Journal of Neural Engineering  ·  01 Sep 2009  ·  doi:10.1088/1741-2560/6/5/055009
Altered mechanosensitive properties of vagal afferent fibers innervating the stomach following gastric surgery in rats
Altered mechanosensitive properties of vagal afferent fibers innervating the stomach following gastric surgery in rats
A. Miranda, A. Mickle, B. Medda, Z. Zhang, R.J. Phillips, N. Tipnis, T.L. Powley, R. Shaker, J.N. Sengupta
Neuroscience  ·  01 Sep 2009  ·  doi:10.1016/j.neuroscience.2009.05.042